Human vitamin supplements can damage the digestive tract lining, especially those containing iron, and can lead to kidney and liver damage.[citation needed]. Ibuprofen and acetaminophen, commonly known as Motrin or Advil, and Tylenol, can cause liver damage in dogs.
Mycotoxins are poisonous compounds naturally produced by certain types of mold. These toxic substances can accumulate in a dog's body over time, causing damage to vital organs including the liver, kidneys, and nervous system.

Aspergillus flavus produces aflatoxins, which have triggered multiple FDA pet food recalls and can cause fatal liver damage in dogs. Penicillium commonly grows on grain-based kibble ingredients like corn, wheat, and rice.

Ultimately, mycotoxins damage the liver and impair its ability to remove toxins and regulate metabolism, leading to poor performance and even increased mortality in hens.
After mycotoxin poisoning, due to the inhibition of the liver, kidneys and other functional organs and the immune system, there is almost no good way to cure it. This is the same principle as the treatment of fatty liver and liver cirrhosis in humans.