They also found that the conjugate has distinct effects on the activity and protein expression of the hypothalamus, a brain region that regulates satiety and is key to the effects of GLP-1 drugs.
Firstly, to explore the conjugation of a whey milk protein, apo-lactoferrin (Apo-LF), with EGCG. Secondly, to assess the impact of a proteinpolyphenol conjugate on GLP-1 secretion by human colon cells compared to unbound components. The antioxidant activity of the EGCG in the conjugates was also assessed.
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